Methane

Methane

SCHEMBL6578174

C.Cc1cccc(C)c1O.Cc1cccc(C)c1O.Cc1cccc(C)c1O

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.93
TRPA1 O75762 2/20 0.68
GABRA1 P14867 3/20 0.56
GABRB2 P47870 3/20 0.56
HPGD P15428 3/20 0.54
HSD17B10 Q99714 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ATM Q13315 2/20 0.52
CYP1A2 P05177 2/20 0.47
CYP2A6 P11509 1/20 0.47
TSHR P16473 2/20 0.47
ACHE P22303 2/20 0.47
CA2 P00918 5/20 0.45
CA1 P00915 4/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
KMT2A Q03164 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 1/20 0.45
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11575272 0.97 ALDH1A1 (1.00) ALDH1A1TRPA1GABRA1GABRB2HPGD
SCHEMBL64141 0.97
SCHEMBL2500374 0.97 ALDH1A1 (1.00) ALDH1A1TRPA1GABRA1GABRB2HPGD
SCHEMBL29521760 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
SCHEMBL10895566 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
SCHEMBL11411128 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
Hydrochloric Acid SCHEMBL7078680 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
Bromide SCHEMBL30923434 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
Methyl Alcohol SCHEMBL28987720 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD
SCHEMBL2158883 0.93 ALDH1A1 (0.93) ALDH1A1TRPA1GABRA1GABRB2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1080084-B1 PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS DOW GLOBAL TECHNOLOGIES INC (US) 2004-05-06 EP claimed