SCHEMBL6578256

SCHEMBL6578256

OC(c1ccccc1)c1cccc(C(O)c2ccccc2)c1C(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 1/20 0.39
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
GAA P10253 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063846 0.87 MAPT (0.44) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL7809671 0.85 MEN1 (0.63) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL8926585 0.84 KMT2A (0.42) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL4062311 0.79 MEN1 (0.41) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL9193862 0.78 MEN1 (0.52) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL7799164 0.77 MEN1 (0.40) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL29405346 0.76 MAPT (0.50) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL9575839 0.76 MEN1 (0.50) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
SCHEMBL984999 0.76 MAPT (0.50) MEN1MAPTCYP2C9KMT2ASMN1; SMN2
Diphenylmethanol SCHEMBL11564700 0.76 SMN1; SMN2 (0.61) SMN1; SMN2L3MBTL1LMNAMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510545-B1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM SPA (IT) 1996-10-02 EP claimed
US-5236979-A Containing synergistic mixture of tris/hydroxybenzyl/benzene and bis/alkylphenyl/pentaerythritol diphosphite ECP ENICHEM POLIMERI S.R.L. (IT) 1993-08-17 US claimed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP claimed
JP-5125262-A None JP disclosed
WO-2017063849-A1 POLYETHER ESTER BLOCK COPOLYMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-04-20 WO disclosed
EP-0926178-B1 Method to reduce gel formation in PET resin ARTEVA TECH SARL (CH) 2004-05-06 EP disclosed
EP-0926178-A1 Method to reduce gel formation in PET resin HNA Holdings, Inc. (US) 1999-06-30 EP disclosed
EP-0926179-A2 Method to reduce regenerated acetaldehyde in polyester resins HNA Holdings, Inc. (US) 1999-06-30 EP disclosed
US-5874515-A CATALYTIC ESTER INTERCHANGE HOECHST CELANESE CORPORATION (US) 1999-02-23 US disclosed
US-5874517-A ADDITION OF PRIMARY PHENOLIC AND SECONDARY PHOSPHONITE ANTIOXIDANTS EITHER PRIOR TO OR AFTER THE POLYETHYLENE TEREPHTHALATE POLYCONDENSATION REACTION IN ORDER TO REDUCE THE AMOUNT OF REGENERATED ACETALDEHYDE PRODUCED HOECHST CELANESE CORPORATION (US) 1999-02-23 US disclosed
EP-0510545-B1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM SPA (IT) 1996-10-02 EP disclosed
US-5236979-A Containing synergistic mixture of tris/hydroxybenzyl/benzene and bis/alkylphenyl/pentaerythritol diphosphite ECP ENICHEM POLIMERI S.R.L. (IT) 1993-08-17 US disclosed
JP-H05125262-A ELASTOMERIC THERMOPLASTIC COPOLYETHER-ESTER ENDOWED WITH IMPROVED THERMAL AND HYDROLYTIC STABILITIE ECP ENICHEM POLIMERI SRL 1993-05-21 JP disclosed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP disclosed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP disclosed