SCHEMBL6578274

SCHEMBL6578274

CCCCCc1cc2ccccc2c(N)c1CCCCC

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 15/20 0.54
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PARP1 P09874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28222385 0.86 TLR8 (0.52) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL28860556 0.86 TLR8 (0.52) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL28222384 0.86 TLR8 (0.52) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL7532153 0.85 TLR8 (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL29208055 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL3391214 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL6235138 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL10899167 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL3393249 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1
SCHEMBL11587314 0.84 MAPT (0.50) TLR8MAPTKDM4EUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305136-A1 SHAPED TOILET CLEANER BLOCK Unilever IP Holdings B.V. (NL) 2024-01-17 EP disclosed
EP-4305137-A1 SHAPED TOILET CLEANER BLOCK Unilever IP Holdings B.V. (NL) 2024-01-17 EP disclosed
EP-1478722-A1 LIQUID CLEANING COMPOSITIONS UNILEVER N.V. (NL) 2004-11-24 EP disclosed
WO-2003072689-A1 LIQUID CLEANING COMPOSITIONS UNILEVER N.V. (NL) 2003-09-04 WO disclosed
EP-1313833-A1 CLEANING AID UNILEVER N.V. (NL) 2003-05-28 EP disclosed
WO-2002018531-A1 CLEANING AID UNILEVER N.V. (NL) 2002-03-07 WO disclosed