Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.56 |
| ▸ | CTSL | P07711 | 14/20 | 0.56 |
| ▸ | CTSS | P25774 | 13/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580967 | 0.91 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6581112 | 0.90 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6577780 | 0.89 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6582337 | 0.88 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6578194 | 0.85 | CTSK (0.56) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL20915172 | 0.83 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL3046987 | 0.83 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4764918 | 0.83 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6578193 | 0.83 | CTSK (0.48) | CTSKCTSLCTSSCTSB | |
| SCHEMBL3046983 | 0.78 | CTSK (0.56) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |