Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 11/20 | 0.44 |
| ▸ | TOP1 | P11387 | 8/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580651 | 0.94 | KCNH2 (0.49) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL6578831 | 0.90 | CYP3A4 (0.54) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL6578566 | 0.90 | KCNH2 (0.47) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL21341272 | 0.90 | KCNH2 (0.47) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL6578453 | 0.85 | KCNH2 (0.50) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL7007374 | 0.84 | CYP3A4 (0.58) | TOP2ATOP1TOP2BCYP3A4CYP2C9 | |
| SCHEMBL6580734 | 0.84 | CYP3A4 (0.56) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL6578454 | 0.84 | KCNH2 (0.48) | KCNH2TOP2ATOP1TOP2BCYP3A4 | |
| SCHEMBL20912595 | 0.83 | TOP2A (0.43) | TOP2ATOP1TOP2BCYP3A4CYP2C9 | |
| SCHEMBL20912556 | 0.82 | KCNH2 (0.46) | KCNH2TOP2ATOP1TOP2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897919-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6211375-B1 | IMPROVED INTESTINAL ABSORPTION | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0897919-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-02-24 | — | — | EP | disclosed |