Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004439 | 0.88 | KDM4E (0.42) | KDM4EGSK3BHPGDMAPTALDH1A1 | |
| SCHEMBL8001709 | 0.86 | KDM4E (0.42) | KDM4EGSK3BHPGDMAPTALDH1A1 | |
| SCHEMBL8001220 | 0.85 | KDM4E (0.43) | KDM4EHTTSMN1; SMN2GSK3BHPGD | |
| SCHEMBL6582077 | 0.85 | GSK3B (0.42) | KDM4EGSK3BHPGDALDH1A1HSD17B10 | |
| SCHEMBL7988963 | 0.85 | GSK3B (0.42) | KDM4EGSK3BHPGDALDH1A1HSD17B10 | |
| SCHEMBL7998792 | 0.85 | GSK3B (0.42) | KDM4EGSK3BHPGDALDH1A1HSD17B10 | |
| SCHEMBL6579810 | 0.84 | HPGD (0.45) | KDM4ESMN1; SMN2HPGDLMNAHDAC6 | |
| SCHEMBL8001338 | 0.84 | KDM4E (0.40) | KDM4EGSK3BHPGDTP53ALDH1A1 | |
| SCHEMBL7997782 | 0.83 | GSK3B (0.39) | KDM4EGSK3BHPGDMAPTALDH1A1 | |
| SCHEMBL7997311 | 0.83 | POLB (0.43) | KDM4EHTTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |