Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001220 | 0.96 | KDM4E (0.43) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7988858 | 0.91 | ADRA2A (0.44) | POLBMEN1KMT2AADRA2AKDM4E | |
| SCHEMBL7998809 | 0.88 | ADRA2A (0.42) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8000926 | 0.88 | ADRA2A (0.42) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8000745 | 0.88 | ADRA2A (0.44) | POLBMEN1KMT2AADRA2AHPGD | |
| SCHEMBL8001141 | 0.86 | POLB (0.45) | POLBMEN1KMT2AADRA2AKDM4E | |
| SCHEMBL8000524 | 0.86 | KDM4E (0.49) | POLBMEN1KMT2AADRA2AKDM4E | |
| SCHEMBL6581059 | 0.86 | MEN1 (0.46) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8001338 | 0.86 | KDM4E (0.40) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL7999037 | 0.86 | ADRA2A (0.43) | POLBADRA2AKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158265-C | Quinoline ketone derivant and antianaphylaction using same as active substance | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| CN-1095834-C | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1275564-A | Quinoline ketone derivant and antianaphylaction using same as active substance | DAINIPPON INK & CHEMICALS (JP) | 2000-12-06 | — | — | CN | disclosed |
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| CN-1163268-A | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | LAINIPPON INK AND CHEMICALC IN (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |