Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 18/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906001 | 0.78 | BDKRB2 (0.54) | BDKRB2MAPTTHRB | |
| SCHEMBL8361700 | 0.77 | BDKRB2 (0.57) | BDKRB2MAPTTHRB | |
| SCHEMBL6580640 | 0.77 | BDKRB2 (0.42) | BDKRB2MAPTTHRB | |
| SCHEMBL8367539 | 0.76 | GAA (0.49) | BDKRB2MAPTTHRB | |
| SCHEMBL6641880 | 0.75 | BDKRB2 (0.57) | BDKRB2MAPTTHRB | |
| SCHEMBL8367312 | 0.74 | BDKRB2 (0.52) | BDKRB2 | |
| SCHEMBL6576080 | 0.73 | BDKRB2 (0.42) | BDKRB2MAPTTHRB | |
| SCHEMBL6581456 | 0.73 | BDKRB2 (0.46) | BDKRB2MAPTTHRB | |
| SCHEMBL6581233 | 0.71 | KDM4E (0.40) | BDKRB2MAPT | |
| SCHEMBL7016157 | 0.71 | BDKRB2 (0.51) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867432-B1 | Fused N-heterocyclic compounds substituted with benzyloxy, process for their preparation and their use as bradykinin receptor antagonists | AVENTIS PHARMA GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6211196-B1 | 8-BENZYLOXY-(TETRAHYDRO)QUINOLINE DERIVATIVES; LIVER CIRRHOSIS, ALZHEIMER*S DISEASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-03 | — | — | US | disclosed |