Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998971 | 0.92 | MAPT (0.49) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL7989452 | 0.92 | MAPT (0.49) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL7977928 | 0.91 | CNR2 (0.52) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL8004065 | 0.87 | KDM4E (0.44) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL6582097 | 0.86 | CNR2 (0.47) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL7997703 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL7989022 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL7998763 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL8004025 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2ACNR2CNR1 | |
| SCHEMBL8001065 | 0.82 | MAPT (0.48) | MAPTMEN1KMT2ACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |