Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998971 | 0.96 | MAPT (0.49) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7989452 | 0.96 | MAPT (0.49) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8001583 | 0.91 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7998708 | 0.90 | CNR2 (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8001706 | 0.90 | MEN1 (0.46) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6582308 | 0.89 | MAPT (0.47) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6579909 | 0.89 | CYP1A2 (0.51) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL8001946 | 0.88 | CNR2 (0.47) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7987951 | 0.88 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7988296 | 0.88 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |