⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174125 | 0.67 | — | — | |
| SCHEMBL2575806 | 0.61 | — | — | |
| SCHEMBL144636 | 0.55 | — | — | |
| SCHEMBL2901 | 0.50 | — | — | |
| SCHEMBL141370 | 0.50 | — | — | |
| SCHEMBL6640940 | 0.50 | — | — | |
| SCHEMBL4215995 | 0.50 | — | — | |
| SCHEMBL4580233 | 0.50 | — | — | |
| SCHEMBL838578 | 0.50 | — | — | |
| SCHEMBL39657 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120442-A1 | PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | WO | claimed |
| US-20190350239-A1 | LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF | BASF SE (DE) | 2019-11-21 | — | — | US | claimed |
| US-20170265510-A1 | LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF | BASF SE (DE) | 2017-09-21 | — | — | US | claimed |
| EP-1480944-B1 | SUBSTITUTED ARYL KETONES | BAYER IP GMBH (DE) | 2016-08-10 | — | — | EP | claimed |
| US-20130251647-A1 | LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF | BASF SE (DE) | 2013-09-26 | — | — | US | claimed |
| US-7807703-B2 | Herbicides; pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-05 | — | — | US | claimed |
| US-20050288185-A1 | Substituted phenyluracils | BAYER CROPSCIENCE AG (DE) | 2005-12-29 | — | — | US | claimed |
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-07-14 | — | — | US | claimed |
| US-20050090397-A1 | Herbicides made from substituted aryl ketones | BAYER CROPSCIENCE AG (GB) | 2005-04-28 | — | — | US | claimed |
| EP-0266949-B1 | TETRAHYDROISOQUINOLIN-2-YL DERIVATIVES OF CARBOXYLIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-11-28 | — | — | EP | claimed |
| US-4812573-A | ARYLSULFONAMIDE SUBSTITUTED TETRAHYDROISOQUINOLINYLALKANOIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITHKLINE & FRENCH LABORATORIES, LTD. (GB) | 1989-03-14 | — | — | US | claimed |
| EP-0266949-A1 | Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-05-11 | — | — | EP | claimed |
| WO-1988003137-A1 | TETRAHYDROISOQUINOLIN-2-YL DERIVATIVES OF CARBOXYLIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-05-05 | — | — | WO | claimed |
| CN-118339156-A | 2-Diazo-3-oxo-2, 3-dihydrospiro [ indene-1, 9' -xanthene ] derivatives and similar compounds as photoactive fluorescent compounds for protein labelling | 爱康治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118317956-A | Bis (hetero) aryl thioether oxadiazines as fungicidal compounds | 拜耳公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024143452-A1 | 3-METHYL-1-BUTENE-BASED POLYMER, MANUFACTURING METHOD THEREFOR, RESIN COMPOSITION, PELLET, AND MOLDED ITEM | 株式会社クラレ | 2024-07-04 | — | — | WO | disclosed |
| US-4543256-A | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers | NORTHEASTERN UNIVERSITY (US) | 1985-09-24 | — | — | US | disclosed |
| EP-0040074-B1 | N-SUBSTITUTED APORPHINES, A METHOD OF INDUCING EMESIS AND A METHOD OF CONTROLLING PSYCHOSIS UTILISING THE SAME | NORTHEASTERN UNIVERSITY (US) | 1985-07-31 | — | — | EP | disclosed |
| EP-0040074-A1 | N-substituted aporphines, a method of inducing emesis and a method of controlling psychosis utilising the same | NORTHEASTERN UNIVERSITY (US) | 1981-11-18 | — | — | EP | disclosed |
| US-3994922-A | Benzopyrans and intermediates for the preparation of pyrrolo benzopyrans | ARTHUR D. LITTLE, INC. (US) | 1976-11-30 | — | — | US | disclosed |