⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13967198 | 0.75 | — | — | |
| SCHEMBL6485531 | 0.73 | — | — | |
| SCHEMBL229379 | 0.71 | EPHX1 (0.35) | — | |
| SCHEMBL407 | 0.71 | EPHX1 (0.35) | — | |
| SCHEMBL11559324 | 0.65 | — | — | |
| SCHEMBL8664112 | 0.65 | — | — | |
| SCHEMBL965869 | 0.62 | — | — | |
| SCHEMBL9335398 | 0.59 | — | — | |
| SCHEMBL19091768 | 0.58 | — | — | |
| SCHEMBL603469 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214881-A1 | Method for producing optically active halopropanediol derivative | KANEKA CORPORATION (JP) | 2004-10-28 | — | — | US | claimed |
| EP-1422213-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOPROPANEDIOL DERIVATIVE | KANEKA CORPORATION (JP) | 2004-05-26 | — | — | EP | claimed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20140228443-A1 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20040214881-A1 | Method for producing optically active halopropanediol derivative | KANEKA CORPORATION (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1422213-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOPROPANEDIOL DERIVATIVE | KANEKA CORPORATION (JP) | 2004-05-26 | — | — | EP | disclosed |