Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586138 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6579467 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6576522 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6579134 | 0.84 | CYP1A2 (0.41) | SMN1; SMN2MAPTCYP1A2CYP2D6NPC1 | |
| SCHEMBL6576899 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL6579241 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKMT2ATDP1HTT | |
| SCHEMBL6582316 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKMT2ATDP1NPSR1 | |
| SCHEMBL6579171 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTKMT2ATDP1HTT | |
| SCHEMBL6576729 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6579094 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |