Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581436 | 0.92 | LMNA (0.44) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579800 | 0.91 | TSHR (0.44) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579355 | 0.84 | SMN1; SMN2 (0.44) | CYP1A2CYP2D6NPC1LMNAALDH1A1 | |
| SCHEMBL6579313 | 0.84 | SMN1; SMN2 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL7985121 | 0.79 | CNR1 (0.36) | CYP1A2HSD17B10LMNAALDH1A1KDM4E | |
| SCHEMBL6576926 | 0.78 | CYP1A2 (0.38) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6580988 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579039 | 0.77 | ALDH1A1 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579572 | 0.77 | ALDH1A1 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6586138 | 0.77 | SMN1; SMN2 (0.44) | CYP1A2CYP2D6HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |