Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579348 | 0.91 | SMN1; SMN2 (0.45) | MAPTTHRBPOLBTP53ALDH1A1 | |
| SCHEMBL6579338 | 0.91 | SMN1; SMN2 (0.45) | MAPTTHRBPOLBTP53ALDH1A1 | |
| SCHEMBL6579558 | 0.77 | SMN1; SMN2 (0.41) | MAPTTHRBPOLBTP53ALDH1A1 | |
| SCHEMBL6579551 | 0.77 | SMN1; SMN2 (0.41) | MAPTTHRBPOLBTP53ALDH1A1 | |
| SCHEMBL6578885 | 0.76 | MAOB (0.38) | MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6576816 | 0.76 | TRPV1 (0.38) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL6578891 | 0.76 | MAOB (0.38) | MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6576810 | 0.76 | TRPV1 (0.38) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL7975957 | 0.75 | SMN1; SMN2 (0.45) | MAPTTHRBPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7975956 | 0.75 | SMN1; SMN2 (0.45) | MAPTTHRBPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |