Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579888 | 1.00 | HPGD (0.42) | HPGDRECQLTDP1MMP13SMN1; SMN2 | |
| SCHEMBL6581702 | 0.96 | HPGD (0.46) | HPGDRECQLTDP1MMP13SMN1; SMN2 | |
| SCHEMBL6579513 | 0.93 | TDP1 (0.49) | HPGDRECQLTDP1SMN1; SMN2KMT2A | |
| SCHEMBL6576914 | 0.92 | TDP1 (0.44) | HPGDRECQLTDP1MMP13SMN1; SMN2 | |
| SCHEMBL6577324 | 0.88 | KMT2A (0.39) | HPGDRECQLTDP1MMP13SMN1; SMN2 | |
| SCHEMBL6579475 | 0.88 | LMNA (0.41) | HPGDTDP1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6579935 | 0.88 | LMNA (0.41) | HPGDTDP1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6579402 | 0.88 | SMN1; SMN2 (0.48) | HPGDSMN1; SMN2KMT2ATSHRALDH1A1 | |
| SCHEMBL6579930 | 0.86 | TDP1 (0.41) | HPGDRECQLTDP1MMP13SMN1; SMN2 | |
| SCHEMBL6582112 | 0.86 | LMNA (0.41) | HPGDTDP1SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |