Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579645 | 0.90 | AR (0.48) | SMN1; SMN2MAPK1ARMAPTCYP1A2 | |
| SCHEMBL6578922 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPK1MAPTCYP1A2CYP2D6 | |
| SCHEMBL6579278 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1ARMAPTALDH1A1 | |
| SCHEMBL6576729 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1MAPTCYP1A2CYP2D6 | |
| SCHEMBL6580962 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1MAPTCYP1A2CYP2D6 | |
| SCHEMBL6581956 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1ARMAPTCYP1A2 | |
| SCHEMBL6577291 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1MAPTCYP1A2CYP2D6 | |
| SCHEMBL6577257 | 0.78 | L3MBTL1 (0.51) | SMN1; SMN2MAPK1ARMAPTALDH1A1 | |
| SCHEMBL6582192 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1ARMAPTALDH1A1 | |
| SCHEMBL6578789 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1ARMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |