SCHEMBL6579635

SCHEMBL6579635

CC(C)COC(=O)c1cccc(C(=O)O)c1C(=O)OCC(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
TSHR P16473 2/20 0.67
MAPT P10636 3/20 0.50
MEN1 O00255 1/20 0.50
TP53 P04637 1/20 0.50
NPY1R P25929 1/20 0.50
NPY2R P49146 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 1/20 0.45
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
ADRB2 P07550 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7059492 0.93 ALDH1A1 (0.76) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL27586569 0.90 ALDH1A1 (0.71) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL8548113 0.86 ALDH1A1 (0.57) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL8549820 0.86 ALDH1A1 (0.57) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL8548420 0.86 ALDH1A1 (0.57) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL226501 0.85 ALDH1A1 (0.86) ALDH1A1TSHRMAPTMEN1TP53
Phthalic Acid SCHEMBL19667985 0.85 ALDH1A1 (0.86) ALDH1A1TSHRMAPTMEN1TP53
Phthalic Acid SCHEMBL29007201 0.85 ALDH1A1 (0.86) ALDH1A1TSHRMAPTMEN1TP53
Phthalic Acid SCHEMBL29285130 0.85 ALDH1A1 (0.86) ALDH1A1TSHRMAPTMEN1TP53
SCHEMBL29601593 0.85 ALDH1A1 (0.86) ALDH1A1TSHRMAPTMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074725-A Benzene polycarboxylic acid and its improvement method for hydrogenation of derivative 埃克森美孚化学专利公司 2017-08-18 CN disclosed
CN-1241882-C Method for hydrogenating organic compounds by means of RU/SIO2 catalysts BASF AG (DE) 2006-02-15 CN disclosed
CN-1531459-A With Ru/SiO2Method for hydrogenating organic compounds with a catalyst �����ɷ� 2004-09-22 CN disclosed
EP-1412082-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF Aktiengesellschaft (DE) 2004-04-28 EP disclosed
EP-1314714-A2 Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using a catalyst containing macropores BASF AKTIENGESELLSCHAFT (DE) 2003-05-28 EP disclosed
EP-1042273-B1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AG (DE) 2003-05-07 EP disclosed
WO-2002100536-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed
CN-1034010-A Composition of olefin copolymer IDEMITSU PETROCHEMICAL CO (JP) 1989-07-19 CN disclosed