Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525171 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL1524454 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL1524455 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL9451969 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL27671416 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL561968 | 0.79 | NPSR1 (0.62) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL3306367 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL12763787 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL15869132 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL27828437 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412330-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003018556-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-03-06 | — | — | WO | disclosed |