Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581017 | 0.93 | TDP1 (0.33) | ALDH1A1KDM4EMAPTHSD17B10TDP1 | |
| SCHEMBL6581870 | 0.87 | LMNA (0.33) | ALDH1A1KDM4ETDP1HPGDEGFR | |
| SCHEMBL6579279 | 0.86 | LMNA (0.35) | ALDH1A1KDM4ETDP1HPGDTSHR | |
| SCHEMBL6577376 | 0.81 | LMNA (0.33) | ALDH1A1KDM4EMAPTTDP1HPGD | |
| SCHEMBL6581222 | 0.80 | LMNA (0.36) | ALDH1A1KDM4ETDP1HPGDTSHR | |
| SCHEMBL6581167 | 0.78 | LMNA (0.35) | ALDH1A1KDM4EMAPTHSD17B10TDP1 | |
| SCHEMBL6579599 | 0.78 | EGFR (0.31) | ALDH1A1KDM4ETDP1HPGDEGFR | |
| SCHEMBL6579046 | 0.78 | LMNA (0.35) | ALDH1A1KDM4EMAPTHSD17B10TDP1 | |
| SCHEMBL6581131 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHSD17B10TDP1 | |
| SCHEMBL6579571 | 0.76 | TDP1 (0.50) | ALDH1A1KDM4EMAPTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |