Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.46 |
| ▸ | MMP2 | P08253 | 14/20 | 0.46 |
| ▸ | MMP9 | P14780 | 14/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579907 | 1.00 | MMP1 (0.46) | MMP1MMP2MMP9ACHEL3MBTL1 | |
| SCHEMBL6581491 | 0.86 | MMP1 (0.46) | MMP1MMP2MMP9ACHEL3MBTL1 | |
| SCHEMBL6581489 | 0.86 | MMP1 (0.46) | MMP1MMP2MMP9ACHEL3MBTL1 | |
| SCHEMBL6577324 | 0.84 | KMT2A (0.39) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL6581205 | 0.82 | MMP1 (0.43) | MMP1MMP2MMP9L3MBTL1SMN1; SMN2 | |
| SCHEMBL6581198 | 0.82 | MMP1 (0.43) | MMP1MMP2MMP9L3MBTL1SMN1; SMN2 | |
| SCHEMBL6579121 | 0.80 | TP53 (0.46) | ACHEL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL6578709 | 0.80 | TP53 (0.46) | ACHEL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL6578711 | 0.80 | TP53 (0.46) | ACHEL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL6579123 | 0.80 | TP53 (0.46) | ACHEL3MBTL1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |