Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 3/20 | 0.38 |
| ▸ | CPT1A | P50416 | 3/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432511 | 0.92 | OXTR (0.44) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL6583696 | 0.90 | OXTR (0.45) | OXTRAVPR1AMEN1KMT2ACPT2 | |
| SCHEMBL6582214 | 0.90 | OXTR (0.53) | OXTRAVPR1AMEN1KMT2ACPT2 | |
| SCHEMBL5434135 | 0.86 | OXTR (0.38) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL6582507 | 0.85 | MAPT (0.51) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL6582344 | 0.83 | OXTR (0.47) | OXTRAVPR1ACPT2CPT1ACPT1B | |
| SCHEMBL6582219 | 0.82 | PTGDR2 (0.49) | OXTRAVPR1AIP6K1CPT2CPT1A | |
| SCHEMBL5443524 | 0.82 | OXTR (0.52) | OXTRAVPR1AMEN1KMT2ACPT2 | |
| SCHEMBL5443542 | 0.82 | OXTR (0.44) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL5820190 | 0.79 | OXTR (0.66) | OXTRAVPR1AMEN1KMT2ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272468-B1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1272468-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001074775-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI-SYNTHELABO (FR) | 2001-10-11 | — | — | WO | disclosed |