Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580173 | 0.82 | BCHE (0.52) | NR1H4MCHR1MAPTTP53RXFP1 | |
| SCHEMBL6582685 | 0.81 | MAPT (0.63) | NR1H4MAPTTP53RXFP1MEN1 | |
| SCHEMBL6579798 | 0.81 | NR1H4 (0.61) | NR1H4MAPTTP53RXFP1MEN1 | |
| SCHEMBL6581838 | 0.81 | NR1H4 (0.68) | NR1H4MAPTTP53RXFP1MEN1 | |
| SCHEMBL6580317 | 0.80 | NR1H4 (0.67) | NR1H4MAPTTP53RXFP1MEN1 | |
| SCHEMBL6580176 | 0.80 | NR1H4 (0.66) | NR1H4MAPTTP53RXFP1MEN1 | |
| SCHEMBL6580139 | 0.79 | NPC1 (0.63) | MAPTTP53MEN1KMT2ANPC1 | |
| SCHEMBL6581663 | 0.78 | MAPT (0.58) | NR1H4MAPTTP53MEN1KMT2A | |
| SCHEMBL6346820 | 0.77 | KMT2A (0.65) | NR1H4MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7896325 | 0.75 | MCHR1 (0.47) | NR1H4MCHR1MAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |