Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.55 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580317 | 0.99 | NR1H4 (0.67) | NR1H4CYSLTR1RUVBL1MAPTNPC1 | |
| SCHEMBL6581728 | 0.90 | ALOX15 (0.57) | NR1H4NPC1RAB9AKMT2A | |
| SCHEMBL6577799 | 0.88 | ALOX15 (0.57) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9713649 | 0.86 | NR1H4 (0.63) | NR1H4CYSLTR1MAPTNPC1RAB9A | |
| SCHEMBL6579798 | 0.85 | NR1H4 (0.61) | NR1H4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL6582685 | 0.83 | MAPT (0.63) | NR1H4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL22192243 | 0.81 | NR1H4 (0.71) | NR1H4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL6580199 | 0.81 | NR1H4 (0.54) | NR1H4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL3415084 | 0.81 | NR1H4 (0.62) | NR1H4CYSLTR1NPC1RAB9AMEN1 | |
| SCHEMBL6580139 | 0.81 | NPC1 (0.63) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |