Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128954 | 0.90 | POLB (0.38) | KMT2APOLBMEN1ADRA1BBCHE | |
| SCHEMBL4531618 | 0.86 | MEN1 (0.55) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL11052023 | 0.84 | MEN1 (0.53) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL16116452 | 0.79 | — | — | |
| SCHEMBL7279979 | 0.79 | KMT2A (0.42) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL4390120 | 0.75 | MEN1 (0.44) | KMT2APOLBMEN1HTR1ACHRM2 | |
| SCHEMBL9517649 | 0.75 | KMT2A (0.48) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL718815 | 0.75 | MEN1 (0.53) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL7228117 | 0.75 | KMT2A (0.48) | KMT2APOLBMEN1BRD4BRD2 | |
| SCHEMBL14200372 | 0.75 | POLB (0.48) | KMT2APOLBMEN1BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |