Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401086 | 0.87 | ALDH1A1 (0.68) | KDM4CKMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7569662 | 0.87 | ALDH1A1 (0.68) | KDM4CKMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL917056 | 0.87 | POLB (0.54) | POLBRAB9ACYP3A4NR4A1KMT2A | |
| SCHEMBL27676821 | 0.85 | CYP3A4 (0.53) | POLBRAB9ACYP3A4NR4A1KDM4C | |
| SCHEMBL925741 | 0.82 | SMN1; SMN2 (0.57) | POLBRAB9ACYP3A4KDM4CKMT2A | |
| SCHEMBL17365323 | 0.82 | CYP3A4 (0.61) | POLBRAB9ACYP3A4NR4A1KMT2A | |
| SCHEMBL30621955 | 0.82 | SMN1; SMN2 (0.57) | POLBRAB9ACYP3A4KDM4CKMT2A | |
| SCHEMBL6579751 | 0.82 | ALDH1A1 (0.62) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6581661 | 0.82 | ALDH1A1 (0.62) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8445092 | 0.82 | ALDH1A1 (0.62) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |