Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584386 | 0.96 | PPARG (0.49) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6584539 | 0.96 | PPARG (0.49) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6582673 | 0.94 | FFAR1 (0.49) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6583469 | 0.86 | KDR (0.44) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6583779 | 0.85 | KDR (0.53) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL4038141 | 0.82 | KDR (0.67) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL4727180 | 0.82 | PPARG (0.57) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6585532 | 0.81 | PPARG (0.79) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6585536 | 0.81 | PPARG (0.56) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6583875 | 0.81 | PPARG (0.49) | PPARGFFAR1KDRMAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |