Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SCN1A | P35498 | 3/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579988 | 0.93 | CYP1A2 (0.46) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579572 | 0.88 | ALDH1A1 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579039 | 0.88 | ALDH1A1 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL7996804 | 0.87 | CYP1A2 (0.43) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6581109 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6578826 | 0.85 | CYP1A2 (0.39) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579894 | 0.84 | ALDH1A1 (0.40) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6582955 | 0.83 | ALDH1A1 (0.44) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579314 | 0.83 | ALDH1A1 (0.44) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL6579280 | 0.83 | CYP1A2 (0.37) | CYP1A2CYP2D6SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |