SCHEMBL658157

SCHEMBL658157

O=C(O)C(Cl)CCCCCCCCCCCCCCCCCl

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.46
GPR84 Q9NQS5 3/20 0.35
RNPEP Q9H4A4 1/20 0.35
FFAR1 O14842 1/20 0.35
DDAH1 O94760 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
NOS2 P35228 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
CPB2 Q96IY4 1/20 0.32
GSR P00390 1/20 0.32
ALDH1A1 P00352 1/20 0.32
FOLH1 Q04609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5477295 1.00 TBXAS1 (0.46) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL27413119 1.00 TBXAS1 (0.46) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL1034278 1.00 TBXAS1 (0.46) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL11753554 1.00 TBXAS1 (0.46) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL2207820 1.00 TBXAS1 (0.46) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL9679760 0.98 TBXAS1 (0.45) TBXAS1GPR84RNPEPFFAR1DDAH1
Hydrochloric Acid SCHEMBL11771270 0.98 TBXAS1 (0.47) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL11693016 0.98 TBXAS1 (0.43) TBXAS1GPR84RNPEPFFAR1DDAH1
SCHEMBL1706453 0.90
SCHEMBL7753637 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
EP-3911723-B1 TRACTION FLUIDS LUBRIZOL CORP (US) 2024-05-08 EP disclosed
CN-113302266-B Traction fluid 路博润公司 2023-02-24 CN disclosed
US-20220127539-A1 Traction Fluids LUBRIZOL CORP (US) 2022-04-28 US disclosed
CN-107261148-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2021-07-13 CN disclosed
EP-2401348-B1 LUBRICATING COMPOSITIONS CONTAINING THE REACTION PRODUCT OF AN AROMATIC AMINE AND A CARBOXYLIC FUNCTIONALISED POLYMER AND DISPERSANT LUBRIZOL CORP (US) 2017-11-15 EP disclosed
EP-2431448-B1 Lubricating compositions containing the reaction product of an aromatic amine and a carboxylic functionalised polymer and dispersant LUBRIZOL CORP (US) 2017-11-15 EP disclosed
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN disclosed
CN-103826633-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2017-05-24 CN disclosed
US-9644167-B2 Lubricating compositions containing a carboxylic functionalised polymer and dispersant THE LUBRIZOL CORPORATION (US) 2017-05-09 US disclosed
US-4443577-A COLLOIDAL DISPERSE SYSTEM, OVERBASED SALTS THE LUBRIZOL CORPORATION (US) 1984-04-17 US disclosed
US-4436855-A DIISOCYANATE AND ORGANIC PHOSPHATE THE LUBRIZOL CORPORATION (US) 1984-03-13 US disclosed
EP-0094261-A2 One-component moisture curable urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0094196-A2 Two-component urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
US-4345045-A HEAT RESISTANCE DART INDUSTRIES, INC. (US) 1982-08-17 US disclosed
US-4278610-A SALT FORMATION, COMPLEXING NATIONAL RESEARCH LABORATORIES (US) 1981-07-14 US disclosed
EP-0008174-A1 Method of making an organic metal salt or complex NATIONAL RESEARCH LABORATORIES (US) 1980-02-20 EP disclosed
US-3945931-A Utilization of amido-acids for the production of aqueous fluids for the working of metals AQUILA S.P.A. (IT) 1976-03-23 US disclosed
US-3945955-A OPEN-CELLED FOAMS BY MECHANICAL WHIPPING DIAMOND SHAMROCK CORPORATION (US) 1976-03-23 US disclosed