Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584430 | 0.94 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL4023447 | 0.89 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL5659626 | 0.86 | TRPV1 (0.89) | TRPV1 | |
| SCHEMBL5658624 | 0.85 | TRPV1 (0.88) | TRPV1 | |
| SCHEMBL6587146 | 0.83 | ROS1 (0.53) | TRPV1 | |
| SCHEMBL5659714 | 0.83 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL5664749 | 0.82 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL4026884 | 0.81 | TRPV1 (0.87) | TRPV1 | |
| SCHEMBL4030489 | 0.81 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL4029208 | 0.80 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478363-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | Abbott Laboratories (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003070247-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | claimed |