Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6579898 | 0.99 | KMT2A (0.55) | KMT2AMEN1KDM4EALDH1A1SMPD1 | |
| SCHEMBL6577701 | 0.84 | SMPD1 (0.55) | KMT2AMEN1KDM4EALDH1A1SMPD1 | |
| Hydrochloric Acid SCHEMBL6579984 | 0.83 | SMPD1 (0.54) | KMT2AMEN1KDM4EALDH1A1SMPD1 | |
| SCHEMBL6580042 | 0.77 | DRD1 (0.48) | KMT2AKDM4ESMPD1CYP1A2CYP3A4 | |
| SCHEMBL6577273 | 0.77 | CYP1A2 (0.47) | KMT2AKDM4ESMPD1CYP1A2CYP3A4 | |
| SCHEMBL9016259 | 0.77 | KMT2A (0.62) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9016243 | 0.77 | KMT2A (0.66) | KMT2AMEN1KDM4EALDH1A1SMPD1 | |
| Hydrochloric Acid SCHEMBL6581922 | 0.76 | BLM (0.48) | KMT2AMEN1KDM4ESMPD1CYP1A2 | |
| SCHEMBL6581800 | 0.76 | CYP3A4 (0.48) | KMT2AMEN1KDM4ESMPD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6581834 | 0.75 | BLM (0.49) | KMT2AMEN1KDM4ESMPD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737680-B1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0737680-A1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1996-10-16 | — | — | EP | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |