Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016218 | 0.86 | POLB (0.55) | KMT2AMEN1ALDH1A1ADRB2 | |
| SCHEMBL9016236 | 0.82 | KMT2A (0.55) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9330544 | 0.81 | DRD4 (0.52) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL9016231 | 0.80 | MEN1 (0.66) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL9333099 | 0.79 | ABCB1 (0.54) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL9016243 | 0.79 | KMT2A (0.66) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8859222 | 0.78 | ADRB2 (0.69) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL9327600 | 0.77 | CYP1A2 (0.62) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL9338830 | 0.77 | CYP1A2 (0.56) | KMT2AMEN1KDM4EALDH1A1ADRB2 | |
| SCHEMBL6581773 | 0.77 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |