Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584499 | 0.78 | NPY5R (0.56) | CSNK2A2CSNK2A1NPY5RHPGDSCHRNA3 | |
| SCHEMBL6583002 | 0.77 | NPY5R (0.65) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL1666395 | 0.77 | CSNK2A2 (0.90) | CSNK2A2CSNK2A1NPY5RHPGDSCHRNA3 | |
| SCHEMBL7930564 | 0.76 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL1664964 | 0.76 | CSNK2A2 (0.88) | CSNK2A2CSNK2A1NPY5RHPGDSCHRNA3 | |
| SCHEMBL6960853 | 0.75 | CSNK2A2 (0.64) | CSNK2A2CSNK2A1NPY5RHPGDSCHRNA3 | |
| SCHEMBL1663439 | 0.73 | CSNK2A2 (0.82) | CSNK2A2CSNK2A1NPY5RHPGDSPTK2B | |
| SCHEMBL7000363 | 0.73 | NPY5R (1.00) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL7890086 | 0.72 | HTT (0.43) | NPY5RLMNANPC1RAB9A | |
| Iodide SCHEMBL2378107 | 0.71 | CSNK2A2 (0.62) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | claimed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |