Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666395 | 0.80 | CSNK2A2 (0.90) | CSNK2A2CSNK2A1NPY5RMEN1LMNA | |
| SCHEMBL7930564 | 0.79 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL1664964 | 0.79 | CSNK2A2 (0.88) | CSNK2A2CSNK2A1NPY5RMEN1LMNA | |
| SCHEMBL7002169 | 0.78 | NPY5R (0.67) | CSNK2A2CSNK2A1NPY5RMEN1LMNA | |
| SCHEMBL7000363 | 0.78 | NPY5R (1.00) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL896838 | 0.78 | CCNA2 (0.62) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL6958633 | 0.77 | CSNK2A2 (0.56) | CSNK2A2CSNK2A1NPY5RMEN1LMNA | |
| Iodide SCHEMBL2378107 | 0.77 | CSNK2A2 (0.62) | CSNK2A2CSNK2A1NPY5RMAPK1TNIK | |
| SCHEMBL6996444 | 0.76 | NPY5R (0.86) | CSNK2A2CSNK2A1NPY5RMEN1LMNA | |
| SCHEMBL6956624 | 0.76 | NPY5R (0.58) | CSNK2A2CSNK2A1NPY5RKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |