Pyrrolidine

Pyrrolidine

SCHEMBL6582217

C1CCNC1.C1CNCN1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HIF1A Q16665 1/20 0.50
MAPT P10636 1/20 0.50
PDE4A P27815 1/20 0.50
KDR P35968 1/20 0.50
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL8897454 0.96 ALDH1A1 (0.69) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
Azepane SCHEMBL28092886 0.96 ALDH1A1 (0.69) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL10540249 0.96 CXCR4 (0.69) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL11791189 0.96 CXCR4 (0.54) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL8041941 0.93 CXCR4 (0.64) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL8198989 0.92 CXCR4 (0.75) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL8191860 0.92 CXCR4 (0.75) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL6883302 0.92 CXCR4 (0.75) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL2355237 0.92
SCHEMBL1003923 0.92 CXCR4 (0.75) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894499-B Novel natural sulfur-containing alkaloid and preparation method and application thereof 云南民族大学 2024-06-14 CN disclosed
CN-1930649-A Charge storage element and electric double-layer capacitor YOSHIO MASAYUKI (JP) 2007-03-14 CN disclosed
CN-1913899-A Anorectic compounds JAPAN TOBACCO INC (JP) 2007-02-14 CN disclosed
EP-0983054-B1 HAIR GROWTH COMPOSITIONS AND USES GUILFORD PHARM INC (US) 2004-09-15 EP disclosed
US-4098783-A Dye substituted cyclic 1,3-sulfur-nitrogen compounds as dye image-forming materials in photography POLAROID CORPORATION (US) 1978-07-04 US disclosed