Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.57 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582285 | 0.87 | DAO (0.57) | DAOPGRFEN1GABRPGABRD | |
| SCHEMBL6770061 | 0.76 | DAO (0.64) | DAOPGRFEN1GABRPGABRD | |
| SCHEMBL4434568 | 0.76 | DAO (0.52) | DAO | |
| SCHEMBL29464110 | 0.76 | DAO (0.64) | DAOPGRFEN1GABRPGABRD | |
| SCHEMBL7224406 | 0.73 | DAO (0.59) | DAOPGRFEN1GABRPGABRD | |
| SCHEMBL31572449 | 0.73 | DAO (0.64) | DAOPGRFEN1GABRPGABRD | |
| SCHEMBL31481931 | 0.72 | MAOB (0.64) | DAOPGRFEN1MAOB | |
| SCHEMBL29464129 | 0.72 | PGR (0.78) | DAOPGRFEN1MAOB | |
| SCHEMBL2970468 | 0.72 | PGR (0.78) | DAOPGRFEN1MAOB | |
| SCHEMBL6907750 | 0.72 | MAOB (0.64) | DAOPGRFEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |