Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115142 | 0.92 | NPC1 (0.66) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL8113896 | 0.91 | NPC1 (0.61) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL6579892 | 0.90 | NPC1 (0.60) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL28745974 | 0.87 | GAA (0.79) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL6580505 | 0.86 | KMT2A (0.69) | MAPTALDH1A1HPGDHTTPOLB | |
| SCHEMBL2836732 | 0.82 | ALDH1A1 (1.00) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL7244561 | 0.82 | ALDH1A1 (0.72) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL3970194 | 0.81 | F2R (0.58) | MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4658103 | 0.81 | GAA (0.69) | MAPTGAAALDH1A1HPGDHTT | |
| SCHEMBL6577998 | 0.80 | NR1H4 (0.65) | MAPTALDH1A1HTTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |