Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.57 |
| ▸ | CTSL | P07711 | 11/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580092 | 0.87 | CTSK (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582019 | 0.86 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6582431 | 0.85 | CTSK (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580343 | 0.82 | CTSK (0.83) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580440 | 0.81 | CTSK (0.78) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6578148 | 0.80 | CTSK (0.84) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6581988 | 0.78 | CTSK (0.83) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580052 | 0.77 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580316 | 0.77 | CTSK (0.71) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577733 | 0.76 | CTSK (0.71) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |