Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582682 | 0.80 | GRIN2B (0.38) | KDM4EPKMBRD4GRIN2B | |
| SCHEMBL6151213 | 0.79 | GRIN2B (0.51) | KDM4EPKMGRIN2BTGFBR1GPR119 | |
| SCHEMBL29578437 | 0.78 | BRD4 (0.49) | KDM4EPKMBRD4TGFBR1IDO1 | |
| SCHEMBL22944530 | 0.78 | BRD4 (0.49) | KDM4EPKMBRD4TGFBR1IDO1 | |
| SCHEMBL6580888 | 0.78 | SCD (0.43) | GRIN2B | |
| SCHEMBL6583258 | 0.77 | KDM4E (0.53) | KDM4EPKMBRD4GRIN2BFAAH | |
| SCHEMBL6151819 | 0.76 | KDM4E (0.52) | KDM4EPKMBRD4GRIN2BSYK | |
| SCHEMBL6148442 | 0.75 | CYP2D6 (0.64) | KDM4EPKMGRIN2BTGFBR1GPR119 | |
| SCHEMBL3779057 | 0.75 | KDM4E (0.53) | KDM4EPKMGRIN2BFAAHSYK | |
| SCHEMBL4646351 | 0.75 | KDM4E (0.53) | KDM4EPKMBRD4GRIN2BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |