Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6582405 | 0.89 | AVPR1B (0.44) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6580886 | 0.85 | NR1H2 (0.46) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6580906 | 0.85 | NR1H2 (0.46) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| SCHEMBL6584053 | 0.84 | ACP1 (0.46) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6580533 | 0.84 | ACP1 (0.45) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| SCHEMBL6578579 | 0.82 | NR1H3 (0.49) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6581120 | 0.81 | NR1H3 (0.47) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6581321 | 0.81 | NR1H3 (0.48) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6580895 | 0.81 | NR1H3 (0.59) | ACP1AVPR1BHTR7NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL6581053 | 0.81 | NR1H3 (0.51) | ACP1AVPR1BHTR7NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070708-B1 | Triazole derivatives | HOFFMANN LA ROCHE (CH) | 2004-01-14 | — | — | EP | disclosed |
| US-6265426-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-07-24 | — | — | US | disclosed |
| EP-1070708-A1 | Triazole and imidazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-01-24 | — | — | EP | disclosed |