Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585287 | 0.90 | NPY5R (0.71) | NPY5RCCNA2CDK2CCNA1GAA | |
| SCHEMBL6583084 | 0.85 | NPY5R (0.81) | NPY5RCCNA2CDK2CCNA1MAPK8 | |
| SCHEMBL6584850 | 0.84 | NPY5R (0.76) | NPY5RCCNA2CDK2CCNA1TDP1 | |
| SCHEMBL6584650 | 0.79 | NPY5R (1.00) | NPY5RCCNA2CDK2CCNA1GAA | |
| SCHEMBL6581866 | 0.78 | NPY5R (0.78) | NPY5RCCNA2CDK2CCNA1MAPK8 | |
| SCHEMBL6586725 | 0.78 | NPY5R (0.71) | NPY5RCCNA2CDK2CCNA1MAPK8 | |
| SCHEMBL7892690 | 0.75 | L3MBTL1 (0.41) | NPY5RGAATRPM5TDP1MAPK8 | |
| SCHEMBL6583315 | 0.75 | NPY5R (0.62) | NPY5R | |
| SCHEMBL6582913 | 0.74 | NPY5R (0.66) | NPY5RCCNA2CDK2CCNA1MAPK8 | |
| SCHEMBL7001040 | 0.74 | NPY5R (0.80) | NPY5RKMT2AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |