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Cp-609754

Cp-609754

SCHEMBL6583247

C#Cc1cccc(-c2cc(=O)n(C)c3ccc(C(O)(c4ccc(Cl)cc4)c4cncn4C)cc23)c1.C#Cc1cccc(-c2cc(=O)n(C)c3ccc(C(O)(c4ccc(Cl)cc4)c4cncn4C)cc23)c1

nearest known ligand 0.81

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 10/20 0.81
▸ FNTB P49356 10/20 0.81
▸ CYP3A4 P08684 8/20 0.59
▸ RORC P51449 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cp-609754 SCHEMBL4277842 1.00 FNTA (0.81) FNTAFNTBCYP3A4RORC
Cp-609754 SCHEMBL21055098 1.00 FNTA (0.81) FNTAFNTBCYP3A4RORC
Cp-609754 SCHEMBL4299341 1.00 FNTA (0.81) FNTAFNTBCYP3A4RORC
Cp-609754 SCHEMBL1644297 1.00 FNTA (0.81) FNTAFNTBCYP3A4RORC
Cp-609754 SCHEMBL30481066 1.00 FNTA (0.81) FNTAFNTBCYP3A4RORC
SCHEMBL11947163 0.93 FNTA (0.70) FNTAFNTBCYP3A4RORC
SCHEMBL12021644 0.93 FNTA (0.69) FNTAFNTBCYP3A4RORC
SCHEMBL13573622 0.92 FNTA (0.81) FNTAFNTBCYP3A4RORC
SCHEMBL11955976 0.92 FNTA (0.68) FNTAFNTBCYP3A4RORC
SCHEMBL11954234 0.91 FNTA (0.67) FNTAFNTBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395577-A1 CRYSTAL FORMS OF 6- (4-CHLORO-PHENYL)-HYDROXY-(-3-METHYL-3H-IMIDAOL-4-YL)-METHYL]-4-(3-ETHYNYL-PHENYL)-1-METHYL-1H-QUINOLIN-2-ONE, 2,3-DIHYDROXYBUTANEDIOATE SALTS AND METHOD OF PRODUCTION Pfizer Products Inc. (US) 2004-03-10 — — EP disclosed
WO-2002050058-A1 CRYSTAL FORMS OF 6-[(4-CHLORO-PHENYL) -HYDROXY-(-3-METHYL- 3H-IMIDAOL-4-YL) -METHYL] -4-(3-ETHYNYL-PHENYL) -1-METHYL-1H- QUINOLIN-2-ONE, 2,3- DIHYDROXYBUTANEDIOATE SALTS AND METHOD OF PRODUCTION PFIZER PRODUCTS INC. (US) 2002-06-27 — — WO disclosed