Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584254 | 0.91 | PPARG (0.41) | ERBB2PPARGMINK1PDGFRBPDGFRA | |
| SCHEMBL8888965 | 0.89 | PPARG (0.39) | ERBB2PPARGMINK1PDGFRBPDGFRA | |
| SCHEMBL8336422 | 0.87 | ERBB2 (0.34) | ERBB2PPARGMINK1PDGFRBPDGFRA | |
| SCHEMBL8888310 | 0.85 | ERBB2 (0.44) | ERBB2PPARGMINK1 | |
| SCHEMBL6583256 | 0.84 | PPARG (0.48) | ERBB2PPARGMINK1PDGFRBPDGFRA | |
| SCHEMBL6583266 | 0.84 | PPARG (0.48) | ERBB2PPARGMINK1PDGFRBPDGFRA | |
| SCHEMBL6968711 | 0.83 | PTPN1 (0.37) | ERBB2PPARGMINK1MMP2ADAM17 | |
| SCHEMBL8898263 | 0.83 | ERBB2 (0.46) | ERBB2PPARGMINK1 | |
| SCHEMBL8888832 | 0.82 | ERBB2 (0.45) | ERBB2PPARGMINK1 | |
| SCHEMBL8890888 | 0.82 | ERBB2 (0.45) | ERBB2PPARGMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0893995-B1 | ANTICACHECTIC COMPOSITION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6365607-B1 | Anticachectic composition | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-04-02 | — | — | US | disclosed |
| US-6110948-A | Anticachectic composition | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |