Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584254 | 0.98 | PPARG (0.41) | PPARGMTNR1AMTNR1BERBB2MINK1 | |
| SCHEMBL6585823 | 0.93 | PPARG (0.37) | PPARGMTNR1AMTNR1BERBB2MINK1 | |
| SCHEMBL6583264 | 0.89 | ERBB2 (0.35) | PPARGERBB2MINK1MAPTALDH1A1 | |
| SCHEMBL8898263 | 0.86 | ERBB2 (0.46) | PPARGERBB2MINK1 | |
| SCHEMBL8888832 | 0.86 | ERBB2 (0.45) | PPARGERBB2MINK1 | |
| SCHEMBL8890888 | 0.86 | ERBB2 (0.45) | PPARGERBB2MINK1 | |
| SCHEMBL6583455 | 0.85 | PPARG (0.37) | PPARGMTNR1AMTNR1BMAPTHDAC1 | |
| SCHEMBL6585075 | 0.85 | PPARG (0.55) | PPARGMTNR1AMTNR1BERBB2MINK1 | |
| SCHEMBL6585081 | 0.85 | PPARG (0.55) | PPARGMTNR1AMTNR1BERBB2MINK1 | |
| SCHEMBL6975089 | 0.85 | PPARG (0.39) | PPARGMTNR1AMTNR1BERBB2MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |