Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | DHFR | P00374 | 4/20 | 0.44 |
| ▸ | TYMS | P04818 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582558 | 0.91 | NAMPT (0.49) | NAMPTDHFRTYMS | |
| SCHEMBL6582245 | 0.90 | NAMPT (0.51) | NAMPTDHFRTYMS | |
| SCHEMBL6586178 | 0.90 | NAMPT (0.47) | NAMPTDHFRTYMS | |
| SCHEMBL6582181 | 0.85 | NAMPT (0.46) | NAMPTDHFRTYMS | |
| SCHEMBL6584027 | 0.84 | NAMPT (0.55) | NAMPTDHFR | |
| SCHEMBL6580453 | 0.79 | NAMPT (0.50) | NAMPTDHFRTYMS | |
| SCHEMBL6580499 | 0.78 | NAMPT (0.51) | NAMPTDHFRTYMS | |
| SCHEMBL6582221 | 0.78 | NAMPT (0.65) | NAMPT | |
| SCHEMBL14472534 | 0.77 | DHFR (0.41) | NAMPTDHFRTYMS | |
| SCHEMBL6583262 | 0.76 | NAMPT (0.56) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155012-B1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER REC TECH LTD (GB) | 2004-04-14 | — | — | EP | disclosed |
| US-6699861-B1 | ANTI-CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-02 | — | — | US | disclosed |
| EP-1155012-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | Cancer Research Ventures Limited (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050417-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER RESEARCH VENTURES LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |