Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585583 | 0.93 | PPARG (0.61) | PPARGFFAR1PPARASMN1; SMN2KDM4E | |
| SCHEMBL6586240 | 0.85 | PPARG (0.68) | PPARGFFAR1PPARATP53SMN1; SMN2 | |
| SCHEMBL6583405 | 0.84 | FFAR1 (0.41) | PPARGFFAR1PPARATP53SMN1; SMN2 | |
| SCHEMBL8889627 | 0.81 | PPARG (0.50) | PPARGSMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL6587576 | 0.80 | PPARG (0.58) | PPARGKDM4ELMNAMAPTHSD17B10 | |
| SCHEMBL6583684 | 0.78 | SIRT2 (0.47) | PPARGSMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL6584250 | 0.78 | PPARG (0.58) | PPARGMAPTHSD17B10 | |
| SCHEMBL6584259 | 0.78 | PPARG (0.58) | PPARGMAPTHSD17B10 | |
| SCHEMBL6584568 | 0.78 | PPARG (0.68) | PPARGFFAR1PPARAPPARD | |
| SCHEMBL6584211 | 0.78 | PPARG (0.57) | PPARGPPARATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |