Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583397 | 0.93 | PPARG (0.52) | PPARGFFAR1PPARASMN1; SMN2LMNA | |
| SCHEMBL6587576 | 0.88 | PPARG (0.58) | PPARGMTNR1AMTNR1BLMNAAPP | |
| SCHEMBL6584250 | 0.85 | PPARG (0.58) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6584259 | 0.85 | PPARG (0.58) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6584211 | 0.85 | PPARG (0.57) | PPARGPPARAMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL6969220 | 0.84 | PTPN1 (0.44) | PPARGFFAR1PPARAMTNR1AMTNR1B | |
| SCHEMBL6585532 | 0.84 | PPARG (0.79) | PPARGFFAR1PPARASMN1; SMN2MAPT | |
| SCHEMBL6585594 | 0.83 | PPARG (0.42) | PPARGFFAR1PPARAMTNR1AMTNR1B | |
| SCHEMBL6585075 | 0.83 | PPARG (0.55) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6585081 | 0.83 | PPARG (0.55) | PPARGMTNR1AMTNR1BAPPSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |