Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.64 |
| ▸ | CA2 | P00918 | 11/20 | 0.64 |
| ▸ | CA12 | O43570 | 10/20 | 0.64 |
| ▸ | CA7 | P43166 | 10/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 10/20 | 0.64 |
| ▸ | CA9 | Q16790 | 8/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | APOB | P04114 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008813 | 1.00 | CA1 (0.64) | CA1CA2CA12CA7CA14 | |
| Hydrochloric Acid SCHEMBL11453887 | 0.98 | CA1 (0.62) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4641731 | 0.85 | CA1 (0.47) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6198196 | 0.84 | CA1 (0.47) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4231484 | 0.84 | CA1 (0.47) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6559473 | 0.84 | CA1 (0.68) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6199831 | 0.84 | CA1 (0.47) | CA1CA2CA12CA7CA14 | |
| Hydrochloric Acid SCHEMBL6203124 | 0.83 | CA1 (0.46) | CA1CA2CA12CA7CA14 | |
| Hydrochloric Acid SCHEMBL6203128 | 0.83 | CA1 (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL9505624 | 0.81 | CA1 (0.63) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| EP-1097129-A1 | N-BENZOCYCLOALKYL-AMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS | Novartis AG (CH) | 2001-05-09 | — | — | EP | disclosed |
| US-6197798-B1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |
| WO-2000005201-A1 | N-BENZOCYCLOALKYL-AMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2000-02-03 | — | — | WO | disclosed |
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |
| US-4963587-A | ANTICOAGULANT | TANABE SEIYAKU CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0377977-A1 | Glycine derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-18 | — | — | EP | disclosed |