SCHEMBL9505624

SCHEMBL9505624

CC(=O)NC1Cc2ccc(O)cc2C1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.63
CA2 P00918 8/20 0.63
CA12 O43570 3/20 0.63
CA7 P43166 3/20 0.63
CA14 Q9ULX7 3/20 0.63
CA9 Q16790 2/20 0.61
ACHE P22303 4/20 0.55
MTNR1A P48039 4/20 0.53
MTNR1B P49286 2/20 0.53
DRD3 P35462 2/20 0.47
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
APOB P04114 1/20 0.44
MTTP P55157 1/20 0.44
MCHR1 Q99705 1/20 0.43
HSD17B1 P14061 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976285 0.87 CA1 (0.72) CA1CA2CA12CA7CA14
SCHEMBL9669811 0.87 CA1 (0.72) CA1CA2CA12CA7CA14
SCHEMBL11444221 0.85 CA1 (0.61) CA1CA2CA12CA7CA14
SCHEMBL4782371 0.84 CA1 (0.52) CA1CA2CA12CA7CA14
SCHEMBL3858010 0.81 CA1 (0.61) CA1CA2CA12CA7CA14
SCHEMBL6583483 0.81 CA1 (0.64) CA1CA2CA12CA7CA14
SCHEMBL31637765 0.81 CA1 (0.61) CA1CA2CA12CA7CA14
SCHEMBL8008813 0.81 CA1 (0.64) CA1CA2CA12CA7CA14
SCHEMBL4808483 0.81 CA1 (0.61) CA1CA2CA12CA7CA14
SCHEMBL10405252 0.81 CA1 (0.61) CA1CA2CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330380-B1 NOVEL INDANOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 1993-06-23 EP disclosed
US-4975460-A INHIBITION OF PLATELET AGGREGATION TANABE SEIYAKU CO., LTD. (JP) 1990-12-04 US disclosed
EP-0330380-A2 Novel indanoxyacetic acid derivatives and processes for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1989-08-30 EP disclosed