Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42805 | 0.85 | CA12 (0.48) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL29779691 | 0.85 | CA12 (0.48) | CA9CASP1CASP7HSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL2476978 | 0.83 | CA12 (0.47) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL2062134 | 0.83 | CA9 (0.56) | CA9CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL264473 | 0.81 | ADRA2A (0.47) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL21033028 | 0.79 | HSD17B10 (0.48) | CA9CASP1CASP7HSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL8980397 | 0.79 | ADRA2A (0.45) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL21765305 | 0.79 | HSD17B10 (0.48) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL20776763 | 0.79 | HSD17B10 (0.48) | CA9CASP1CASP7HSD17B10CA12 | |
| SCHEMBL4684525 | 0.79 | HSD17B10 (0.48) | CA9CASP1CASP7HSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |